BDBM18739 6-(2-methoxyphenyl)-2,2-dimethyl-4-(1-{[(2E)-3-phenylprop-2-en-1-yl]oxy}ethyl)-1,2-dihydroquinoline::dihydroquinoline-based ligand, 28

SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OC\C=C\c3ccccc3)c2c1

InChI Key InChIKey=XLEGIUMNLZUICH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18739   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18739(6-(2-methoxyphenyl)-2,2-dimethyl-4-(1-{[(2E)-3-phe...)
Affinity DataIC50: 980nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2007
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18739(6-(2-methoxyphenyl)-2,2-dimethyl-4-(1-{[(2E)-3-phe...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2007
Entry Details Article
PubMed