BDBM18751 US8846658, 92::US8846658, 93

SMILES Cc1cc(Cl)cnc1C(=O)Nc1ccc(F)c(c1)[C@]1(CF)COCC(N)=N1

InChI Key InChIKey=NQNLROFWOGGJGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18751   

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM18751(US8846658, 92 | US8846658, 93)
Affinity DataIC50: 5nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM18751(US8846658, 92 | US8846658, 93)
Affinity DataIC50: 8nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent