BDBM18923 2-(3,5-dichloro-4-{4-hydroxy-3-[4-(trifluoromethyl)phenyl]phenoxy}phenyl)acetic acid::4-hydroxy thyromimetic, 9d

SMILES OC(=O)Cc1cc(Cl)c(Oc2ccc(O)c(c2)-c2ccc(cc2)C(F)(F)F)c(Cl)c1

InChI Key InChIKey=UGVNVZOKSDTCKR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18923   

TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18923(2-(3,5-dichloro-4-{4-hydroxy-3-[4-(trifluoromethyl...)
Affinity DataIC50: 67nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18923(2-(3,5-dichloro-4-{4-hydroxy-3-[4-(trifluoromethyl...)
Affinity DataIC50: 67.6nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18923(2-(3,5-dichloro-4-{4-hydroxy-3-[4-(trifluoromethyl...)
Affinity DataIC50: 515nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2007
Entry Details Article
PubMed