BDBM18944 2-{3,5-dibromo-4-[4-hydroxy-3-(3-hydroxyphenoxy)phenoxy]phenyl}acetic acid::4-hydroxy thyromimetic, 13g

SMILES OC(=O)Cc1cc(Br)c(Oc2ccc(O)c(Oc3cccc(O)c3)c2)c(Br)c1

InChI Key InChIKey=WCRWBJJFDPTIQX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18944   

TargetThyroid hormone receptor beta(Human)
University of Insubria

Curated by ChEMBL
LigandPNGBDBM18944(2-{3,5-dibromo-4-[4-hydroxy-3-(3-hydroxyphenoxy)ph...)
Affinity DataIC50: 46.8nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of Insubria

Curated by ChEMBL
LigandPNGBDBM18944(2-{3,5-dibromo-4-[4-hydroxy-3-(3-hydroxyphenoxy)ph...)
Affinity DataIC50: 46.8nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of Insubria

Curated by ChEMBL
LigandPNGBDBM18944(2-{3,5-dibromo-4-[4-hydroxy-3-(3-hydroxyphenoxy)ph...)
Affinity DataIC50: 47nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18944(2-{3,5-dibromo-4-[4-hydroxy-3-(3-hydroxyphenoxy)ph...)
Affinity DataIC50: 549nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18944(2-{3,5-dibromo-4-[4-hydroxy-3-(3-hydroxyphenoxy)ph...)
Affinity DataIC50: 550nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed