BDBM18965 1-[3-(aminomethyl)phenyl]-3-methyl-N-[4-(2-sulfamoylphenyl)phenyl]-1H-pyrazole-5-carboxamide::CHEMBL134736::pyrazole-based inhibitor, 15a
SMILES Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)n(n1)-c1cccc(CN)c1
InChI Key InChIKey=RPHPZHQLDZECGT-UHFFFAOYSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 18965
Affinity DataKi: 2.70nM ΔG°: -11.6kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were determined ...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:In vitro activity against rabbit FXa.More data for this Ligand-Target Pair
Affinity DataKi: 248nM ΔG°: -8.91kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were determined ...More data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:In vitro activity against human trypsin.More data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Tested in vitro for inhibition of human trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+3nMAssay Description:In vitro for inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+4nMAssay Description:In vitro activity against human thrombin.More data for this Ligand-Target Pair