BDBM190226 US9175000, 6
SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35C[C@@H]1[C@](O)(CC(O)CO)c1ccccc1)OC
InChI Key InChIKey=CNTAUNWPRVDTGK-RQFDAPRJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 190226
Affinity DataKi: 12.9nMpH: 7.4Assay Description:Membranes from recombinant HEK-293 cells expressing the human κ opioid receptor (cloned in house) were prepared by lysing cells in ice cold hypo...More data for this Ligand-Target Pair
Affinity DataKi: 49.9nM ΔG°: -10.8kcal/molepH: 7.4 T: 50°CAssay Description:Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membran...More data for this Ligand-Target Pair
Affinity DataEC50: 122nMpH: 7.4 T: 25°CAssay Description:Membranes from recombinant HEK-293 cells, CHO cells expressing the
recombinant human kappa opioid receptor (kappa) were prepared by lysing
cells in...More data for this Ligand-Target Pair
Affinity DataEC50: 196nMpH: 7.4 T: 25°CAssay Description:[35S]GTPgammaS functional assays were conducted using freshly thawed
pt-receptor membranes prepared in-house from a cell line expressing
recombinan...More data for this Ligand-Target Pair