BDBM190985 US10077266, Example 98::US9181249, 98::US9708313, 98

SMILES O=C3NC[C@H](C(=O)N[C@H](C1=C(F)C(Cl)C(F)C=C1)[C@@H]2CC[C@@H](C(F)(F)F)CO2)N3

InChI Key InChIKey=NCBHSJWWCRASPE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 190985   

TargetSodium channel protein type 8 subunit alpha(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 190985BDBM190985((S)—N—((R or S)-(3-chloro-2,4-difluorophenyl)((2S,...)
Affinity DataIC50: 9.5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2026
Entry Details
US Patent