BDBM191228 US9181266, 97

SMILES COc1ccc(C(=O)C2CCN(CC(=O)NCc3cc4c(c(=O)[nH]3)COCC4)CC2)cc1

InChI Key InChIKey=HFAGPKBDTDCMJD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 191228   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 191228BDBM191228(US9181266, 97)
Affinity DataIC50: 27nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 191228BDBM191228(US9181266, 97)
Affinity DataIC50: 100nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 191228BDBM191228(US9181266, 97)
Affinity DataIC50: 1.15E+3nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 191228BDBM191228(US9181266, 97)
Affinity DataIC50: 7.50E+3nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
US Patent