BDBM191655 US9186360, 62::US9186360, 66

SMILES Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1cc(F)c(OCC(C)(C)C)c(F)c1

InChI Key InChIKey=GXZJAPWOZROTCB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 191655   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191655(US9186360, 66 | US9186360, 62)
Affinity DataIC50: 3.63nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191655(US9186360, 66 | US9186360, 62)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily V member 3(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191655(US9186360, 66 | US9186360, 62)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191655(US9186360, 66 | US9186360, 62)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191655(US9186360, 66 | US9186360, 62)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent