BDBM191656 US9186360, 75

SMILES CC(C)COc1c(Cl)cc(cc1Cl)-c1csc(NC(=O)Cc2c(C)oc3n(C)c(=O)n(C)c(=O)c23)n1

InChI Key InChIKey=HFTZDURZNKGJNR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 191656   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191656(US9186360, 75)
Affinity DataIC50: 3.34nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191656(US9186360, 75)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily V member 3(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191656(US9186360, 75)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191656(US9186360, 75)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191656(US9186360, 75)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent