BDBM191867 US10526329, Compound 72::US11072611, Compound 72::US9670204, 72 N-(2-ethyl-6-(1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl)imidazo[1,2-a]pyridin-3-yl)-N-methyl-4-(4-(trifluoromethoxy)phenyl)thiazol-2-amine

SMILES CCc1nc2ccc(cn2c1N(C)c1nc(cs1)-c1ccc(OC(F)(F)F)cc1)C1=CCN(CC1)S(C)(=O)=O

InChI Key InChIKey=WWGAYPJNYISEMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191867   

TargetAutotaxin(Human)
Galapagos

US Patent
LigandPNGBDBM191867(US9670204, 72 N-(2-ethyl-6-(1-(methylsulfonyl)-1,2...)
Affinity DataIC50: 300nMAssay Description:TABLE V: 5 μL of a dilution series of compound, starting from 20 μM highest concentration, 1/5 dilution, is added to the wells. hENPP2 is u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2022
Entry Details
US Patent

TargetAutotaxin(Human)
Galapagos

US Patent
LigandPNGBDBM191867(US9670204, 72 N-(2-ethyl-6-(1-(methylsulfonyl)-1,2...)
Affinity DataIC50: 300nMpH: 8.5 T: 2°CAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate. 5 μL of a di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetAutotaxin(Human)
Galapagos

US Patent
LigandPNGBDBM191867(US9670204, 72 N-(2-ethyl-6-(1-(methylsulfonyl)-1,2...)
Affinity DataIC50: 300nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2020
Entry Details
US Patent