BDBM192231 US9187441, KK229

SMILES CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(N[C@@H](CC(C)C)C(=O)OC)C(=O)NCc1ccccc1

InChI Key InChIKey=GJMKTNWSIDZAMQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192231   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Pittsburgh

US Patent
LigandChemical structure of BindingDB Monomer ID 192231BDBM192231(US9187441, KK229)
Affinity DataKi:  1.70E+3nM ΔG°:  -7.58kcal/molepH: 7.4 T: 2°CAssay Description:All NMR spectra were acquired at 298 K on a Bruker DRX 600 MHz spectrometer equipped with a cryoprobe. Typically, NMR samples contained 0.1-0.2 mM pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent