BDBM192320 US9187459, 5

SMILES CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC12CC1COC2

InChI Key InChIKey=VPBAXWOWGZTFTQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192320   

TargetEpidermal growth factor receptor(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM192320(US9187459, 5)
Affinity DataIC50: 0.370nMT: 2°CAssay Description:1) The compound is dissolved in DMSO to prepare a 10 mM solution, and was diluted to 100 micoM with water. When used for IC50 measurement, series dil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM192320(US9187459, 5)
Affinity DataIC50: 91nMT: 2°CAssay Description:1) The compound is dissolved in DMSO to prepare a 10 mM solution, and was diluted to 100 micoM with water. When used for IC50 measurement, series dil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent