BDBM192447 US9187466, 20::US9687476, 20

SMILES O[C@@H](Cn1c(nn(Cc2nnc(s2)-c2ccccc2C(F)(F)F)c1=O)-c1ccc(Cl)cc1)C(F)(F)F

InChI Key InChIKey=GRJNKBDCMVJZIA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 192447   

TargetVasopressin V1a receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM192447(US9187466, 20 | US9687476, 20)
Affinity DataIC50: 46nMAssay Description:On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM192447(US9187466, 20 | US9687476, 20)
Affinity DataIC50: 46nMT: 2°CAssay Description:On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

TargetVasopressin V2 receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM192447(US9187466, 20 | US9687476, 20)
Affinity DataIC50: 150nMT: 2°CAssay Description:On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

TargetVasopressin V2 receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM192447(US9187466, 20 | US9687476, 20)
Affinity DataIC50: 150nMAssay Description:On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent