BDBM192531 US9187480, 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(trifluoromethanesulfonylmethyl)piperidin-1-yl]-9H-purine

SMILES FC(F)(F)S(=O)(=O)NC1CCN(CC1)c1ncnc2n(c(nc12)-c1ccccc1Cl)-c1ccc(Cl)cc1

InChI Key InChIKey=ZKHONUIMXURESB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 192531   

TargetCannabinoid receptor 1(Human)
Research Triangle Institute

US Patent
LigandPNGBDBM192531(US9187480, 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6...)
Affinity DataKi:  6.10nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Research Triangle Institute

US Patent
LigandPNGBDBM192531(US9187480, 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM192531(US9187480, 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6...)
Affinity DataKi:  4.50E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor (unknown origin) expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM192531(US9187480, 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6...)
Affinity DataKi:  4.50E+3nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent