BDBM192637 US9187486, 76

SMILES C[C@@H]1[C@@H](N)CCCN1c1ccncc1Nc1ncc2ccc(nn12)-c1ncccc1F

InChI Key InChIKey=CMCGBWKSQYENCR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192637   

TargetSerine/threonine-protein kinase pim-1(Human)
Amgen

US Patent
LigandPNGBDBM192637(US9187486, 76)
Affinity DataIC50: 0.300nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Amgen

US Patent
LigandPNGBDBM192637(US9187486, 76)
Affinity DataIC50: 1.80nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent