BDBM192648 US9187486, 100
SMILES C[C@@H]1CCN(C[C@H]1N)c1ccncc1Nc1ncc2ccc(nn12)-c1c(F)cccc1F
InChI Key InChIKey=YAJGELPVDBECTQ-RDTXWAMCSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 192648
Affinity DataIC50: <0.100nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Affinity DataIC50: 212nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of recombinant Pim1 (unknown origin) by electrochemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Inhibition of recombinant Pim2 (unknown origin) by electrochemiluminescence assayMore data for this Ligand-Target Pair