BDBM192796 US9187487, 32

SMILES CN(C)C(=O)C(=Cc1ccc(Oc2cnc3[nH]ccc3n2)cc1)C#N

InChI Key InChIKey=MQIPKMCXOXLLSA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192796   

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Principia Biopharma

US Patent
LigandPNGBDBM192796(US9187487, 32)
Affinity DataIC50: 320nMpH: 7.5 T: 2°CAssay Description:Phosphorylation of the appropriate peptide substrate (fluorescently labeled Srctide) by recombinant JAK3 (catalytic domain, aa 781-1124) was measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2016
Entry Details
US Patent