BDBM192817 US9187487, 82

SMILES CC(C)(C)C(=O)c1c[nH]c2ncc(Nc3ccc(C=C(C#N)c4nccs4)cc3)nc12

InChI Key InChIKey=DGQPXPZJCIMXGK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192817   

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Principia Biopharma

US Patent
LigandPNGBDBM192817(US9187487, 82)
Affinity DataIC50: 38.3nMpH: 7.5 T: 2°CAssay Description:Phosphorylation of the appropriate peptide substrate (fluorescently labeled Srctide) by recombinant JAK3 (catalytic domain, aa 781-1124) was measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2016
Entry Details
US Patent