BDBM192821 US9187487, 88

SMILES CN(C)CCN1C(=O)SC(=Cc2ccc(Nc3cnc4[nH]cc(C(=O)C(C)(C)C)c4n3)cc2)C1=O

InChI Key InChIKey=KKOWZZGJBVAZER-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192821   

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Principia Biopharma

US Patent
LigandPNGBDBM192821(US9187487, 88)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Phosphorylation of the appropriate peptide substrate (fluorescently labeled Srctide) by recombinant JAK3 (catalytic domain, aa 781-1124) was measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2016
Entry Details
US Patent