BDBM193040 (S)-N-((R or S)-(3- chloro-4-(trifluoro- methoxy)phenyl)(1- (trifluoromethyl)- 1H-pyrazol-4- yl)methyl)-2- oxooxazolidine-5- carboxamide::US12516046, Example 53B

SMILES Cn3cc(C(NC(=O)[C@@H]1CNC(=O)O1)c2ccc(OC(F)(F)F)c(Cl)c2)cn3

InChI Key InChIKey=JVCSGMSQXDDVKB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193040   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 193040BDBM193040((S)-N-((R or S)-(3- chloro-4-(trifluoro- methoxy)p...)
Affinity DataIC50: 1.20nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2026
Entry Details
US Patent