BDBM193377 2-(4-(((5-(4-fluorophenyl)-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)methyl)amino)phenyl)acetonitrile::US9676782, 26

SMILES Fc1ccc(cc1)N1CCn2nc(CNc3ccc(cc3)C#C)cc2C1=O

InChI Key InChIKey=LRGBMAZPUPNXDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193377   

TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM193377(2-(4-(((5-(4-fluorophenyl)-4-oxo-4,5,6,7-tetrahydr...)
Affinity DataIC50: 890nMT: 2°CAssay Description:HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM193377(2-(4-(((5-(4-fluorophenyl)-4-oxo-4,5,6,7-tetrahydr...)
Affinity DataIC50: 3.00E+4nMT: 2°CAssay Description:Gα15/TREx cells stably expressing rat mGlu3 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent