BDBM194479 US9200016, 161::US9902710, Compound 161

SMILES COc1cc2cncc(Cc3cnc4ccc(O)c(c4c3)C(F)(F)F)c2cc1OC

InChI Key InChIKey=PJWVLZATNHNKPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 194479   

LigandPNGBDBM194479(US9200016, 161 | US9902710, Compound 161)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

LigandPNGBDBM194479(US9200016, 161 | US9902710, Compound 161)
Affinity DataIC50: 6nMAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent