BDBM195568 (2E)-5-Methoxy-2-[(5-methylfuran-2-yl)methylidene]-2,3-dihydro-1H-inden-1-one (11n)

SMILES COc1ccc2C(=O)\C(Cc2c1)=C\c1ccc(C)o1

InChI Key InChIKey=IEJAVDWNSNDMRX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 195568   

TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM195568((2E)-5-Methoxy-2-[(5-methylfuran-2-yl)methylidene]...)
Affinity DataIC50: 26nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoforms ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM195568((2E)-5-Methoxy-2-[(5-methylfuran-2-yl)methylidene]...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human MAO-B using kynuramine as substrate incubated for 20 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM195568((2E)-5-Methoxy-2-[(5-methylfuran-2-yl)methylidene]...)
Affinity DataIC50: 4.73E+3nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoforms ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2016
Entry Details Article
PubMed