BDBM196608 (r)-5-(4-fluorophenyl)-2-(((2-fluorophenyl)amino)methyl)-7-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one::US9676782, 42

SMILES C[C@@H]1CN(C(=O)c2cc(CNc3ccccc3F)nn12)c1ccc(F)cc1

InChI Key InChIKey=MEZILEUDZJNPPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196608   

TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM196608((r)-5-(4-fluorophenyl)-2-(((2-fluorophenyl)amino)m...)
Affinity DataIC50: 871nMT: 2°CAssay Description:HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM196608((r)-5-(4-fluorophenyl)-2-(((2-fluorophenyl)amino)m...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Gα15/TREx cells stably expressing rat mGlu3 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent