BDBM196750 (r)-2-(((2,4-difluorophenyl)amino)methyl)-5-(4-fluorophenyl)-7-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one::US9676782, 75

SMILES C[C@@H]1CN(C(=O)c2cc(CNc3ccc(F)cc3F)nn12)c1ccc(F)cc1

InChI Key InChIKey=NRELPWXKSRHCCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196750   

TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM196750((r)-2-(((2,4-difluorophenyl)amino)methyl)-5-(4-flu...)
Affinity DataIC50: 771nMT: 2°CAssay Description:HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM196750((r)-2-(((2,4-difluorophenyl)amino)methyl)-5-(4-flu...)
Affinity DataIC50: 5.83E+3nMT: 2°CAssay Description:Gα15/TREx cells stably expressing rat mGlu3 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent