BDBM197078 US9216182, 1.24

SMILES COC(=O)c1cccnc1N1CCC(CC1)OC(=O)N1CCN(CC1)C(C)C

InChI Key InChIKey=PZVRMJPGVUTMGK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197078   

TargetHistamine H3 receptor(Human)
Novartis

US Patent
LigandPNGBDBM197078(US9216182, 1.24)
Affinity DataKi:  1.70nMAssay Description:The potency of compounds of the invention as H3 receptor antagonists can be assessed by measuring the blockade of (R)-alpha-methylhistamine-mediated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Novartis

US Patent
LigandPNGBDBM197078(US9216182, 1.24)
Affinity DataKi:  15nMpH: 7.5Assay Description:The affinity of compounds of the invention to the H3 receptor can be assessed by measuring displacement of binding of the radioligand [3H]-N- ±-Methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details
US Patent