BDBM197127 US9216182, 1.73

SMILES O=C(OC1CCN(CC1)c1ccn2ccnc2c1)N1CCN(CC1)C1CCC1

InChI Key InChIKey=OMZYNNHBHJMMMY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197127   

TargetHistamine H3 receptor(Human)
Novartis

US Patent
LigandPNGBDBM197127(US9216182, 1.73)
Affinity DataKi:  0.400nMAssay Description:The potency of compounds of the invention as H3 receptor antagonists can be assessed by measuring the blockade of (R)-alpha-methylhistamine-mediated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Novartis

US Patent
LigandPNGBDBM197127(US9216182, 1.73)
Affinity DataKi:  2.70nMpH: 7.5Assay Description:The affinity of compounds of the invention to the H3 receptor can be assessed by measuring displacement of binding of the radioligand [3H]-N- ±-Methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details
US Patent