BDBM197180 BDBM197208::US9090621, 7

SMILES CC(C)(C)C=C(C#N)C(=O)N1CCCC(C1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12

InChI Key InChIKey=BRHJRWOQJXUVRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197180   

TargetTyrosine-protein kinase BTK(Human)
Principia Biopharma

US Patent
LigandPNGBDBM197180(US9090621, 7 | BDBM197208)
Affinity DataIC50: 1.30nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of Formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2016
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Principia Biopharma

US Patent
LigandPNGBDBM197180(US9090621, 7 | BDBM197208)
Affinity DataIC50: 2.70nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of Formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2016
Entry Details
US Patent