BDBM197195 US9090621, 37A

SMILES Nc1ncnc2n(nc(-c3ccc(Oc4cc(F)ccc4F)cc3)c12)[C@@H]1CCCN(C1)C(=O)C(=CC1CC1)C#N

InChI Key InChIKey=YYXRGQMMWYCFKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197195   

TargetTyrosine-protein kinase BTK(Human)
Principia Biopharma

US Patent
LigandPNGBDBM197195(US9090621, 37A)
Affinity DataIC50: 4.20nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of Formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2016
Entry Details
US Patent