BDBM197362 US9216962, CFH449-H

SMILES ONC(=O)CCCCCCNC(=O)c1nc(sc1C1CC1)-c1nc2CCCCc2s1

InChI Key InChIKey=HEXCVAOOHDWROK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 197362   

TargetHistone deacetylase 1(Human)
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM197362(US9216962, CFH449-H)
Affinity DataIC50: 11nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM197362(US9216962, CFH449-H)
Affinity DataIC50: 16nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM197362(US9216962, CFH449-H)
Affinity DataIC50: 49nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent