BDBM197741 US9216986, 2-[2-(6-Fluoro-quinolin-2-yl)-ethyl]-5-methyl-[1,2,4]triazolo[1,5-a]pyridin-8-ol::US9801878, 2-[2-(6-Fluoro-quinolin-2-yl)-ethyl]-5-methyl-[1,2,4]triazolo[1,5-a]pyridin-8-ol

SMILES Cc1ccc(O)c2nc(CCc3ccc4cc(F)ccc4n3)nn12

InChI Key InChIKey=SISLFPKXUFKGCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197741   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM197741(US9216986, 2-[2-(6-Fluoro-quinolin-2-yl)-ethyl]-5-...)
Affinity DataIC50:  18nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779](Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM197741(US9216986, 2-[2-(6-Fluoro-quinolin-2-yl)-ethyl]-5-...)
Affinity DataIC50:  85nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent