BDBM19930 3-arylquinazolinone, 1av::5,7-dihydroxy-3-(4-hydroxyphenyl)-2-methyl-3,4-dihydroquinazolin-4-one

SMILES Cc1nc2cc(O)cc(O)c2c(=O)n1-c1ccc(O)cc1

InChI Key InChIKey=HWVMDDZTSAEFOA-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19930   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM19930(5,7-dihydroxy-3-(4-hydroxyphenyl)-2-methyl-3,4-dih...)
Affinity DataIC50: 1.14E+4nM EC50:  1.58E+3nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM19930(5,7-dihydroxy-3-(4-hydroxyphenyl)-2-methyl-3,4-dih...)
Affinity DataIC50: 3.32E+4nMpH: 8.0 T: 2°CAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed