BDBM19943 3-arylquinazolinone, 1aaj::7-hydroxy-3-(4-hydroxyphenyl)-5-methyl-3,4-dihydroquinazolin-4-one

SMILES Cc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12

InChI Key InChIKey=WELNOLGZOJEAHM-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19943   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM19943(7-hydroxy-3-(4-hydroxyphenyl)-5-methyl-3,4-dihydro...)
Affinity DataIC50: 317nM EC50:  136nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM19943(7-hydroxy-3-(4-hydroxyphenyl)-5-methyl-3,4-dihydro...)
Affinity DataIC50: 9.64E+3nM EC50:  2.39E+3nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed