BDBM19947 3-arylquinazolinone, 1aan::5-ethyl-7-hydroxy-3-(4-hydroxyphenyl)-3,4-dihydroquinazolin-4-one

SMILES CCc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12

InChI Key InChIKey=MMOVQWBRRNCTJY-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19947   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM19947(5-ethyl-7-hydroxy-3-(4-hydroxyphenyl)-3,4-dihydroq...)
Affinity DataIC50: 265nM EC50:  62nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM19947(5-ethyl-7-hydroxy-3-(4-hydroxyphenyl)-3,4-dihydroq...)
Affinity DataIC50: 1.32E+4nM EC50:  4.52E+3nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed