BDBM19952 3-arylquinazolinone, 1aas::7-hydroxy-3-(4-hydroxyphenyl)-5-(prop-1-en-2-yl)-3,4-dihydroquinazolin-4-one

SMILES CC(=C)c1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12

InChI Key InChIKey=HXWYZGZFDYRCBN-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19952   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM19952(7-hydroxy-3-(4-hydroxyphenyl)-5-(prop-1-en-2-yl)-3...)
Affinity DataIC50: 2.30E+3nM EC50:  729nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM19952(7-hydroxy-3-(4-hydroxyphenyl)-5-(prop-1-en-2-yl)-3...)
Affinity DataIC50: 4.40E+4nM EC50:  4.26E+3nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed