BDBM19954 3-(3-fluoro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dihydroquinazoline-4-thione::3-arylquinazolinethione, 1bb

SMILES Oc1cc(O)c2c(c1)ncn(-c1ccc(O)c(F)c1)c2=S

InChI Key InChIKey=PXSTXQBNCZBQMC-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19954   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM19954(3-(3-fluoro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dih...)
Affinity DataIC50: 102nM EC50:  20nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM19954(3-(3-fluoro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dih...)
Affinity DataIC50: 3.08E+3nM EC50:  776nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed