BDBM19956 3-arylquinazolinethione, 1bd::7-hydroxy-3-(4-hydroxyphenyl)-5-methyl-3,4-dihydroquinazoline-4-thione

SMILES Cc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=S)c12

InChI Key InChIKey=GHMWCNIIKUZAOU-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19956   

TargetEstrogen receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM19956(7-hydroxy-3-(4-hydroxyphenyl)-5-methyl-3,4-dihydro...)
Affinity DataIC50: 79nMAssay Description:Inhibition of estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM19956(7-hydroxy-3-(4-hydroxyphenyl)-5-methyl-3,4-dihydro...)
Affinity DataIC50: 79nM EC50:  222nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM19956(7-hydroxy-3-(4-hydroxyphenyl)-5-methyl-3,4-dihydro...)
Affinity DataIC50: 1.75E+3nM EC50:  1.67E+3nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed