BDBM199995 US9670231, 1.3::US9670231, 1.34

SMILES CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CC1

InChI Key InChIKey=NECNOKMWRWJOGB-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 199995   

TargetEpidermal growth factor receptor [L858R](Human)
Beigene

US Patent
LigandPNGBDBM199995(US9670231, 1.34 | US9670231, 1.3)
Affinity DataIC50: 0.0790nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

LigandPNGBDBM199995(US9670231, 1.34 | US9670231, 1.3)
Affinity DataIC50: 0.0880nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Beigene

US Patent
LigandPNGBDBM199995(US9670231, 1.34 | US9670231, 1.3)
Affinity DataIC50: 0.700nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

LigandPNGBDBM199995(US9670231, 1.34 | US9670231, 1.3)
Affinity DataIC50: 1.90nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Beigene

US Patent
LigandPNGBDBM199995(US9670231, 1.34 | US9670231, 1.3)
Affinity DataIC50: 7.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Beigene

US Patent
LigandPNGBDBM199995(US9670231, 1.34 | US9670231, 1.3)
Affinity DataIC50: 11nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Beigene

US Patent
LigandPNGBDBM199995(US9670231, 1.34 | US9670231, 1.3)
Affinity DataIC50: 29nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

LigandPNGBDBM199995(US9670231, 1.34 | US9670231, 1.3)
Affinity DataIC50: 119nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Beigene

US Patent
LigandPNGBDBM199995(US9670231, 1.34 | US9670231, 1.3)
Affinity DataIC50: 254nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent