BDBM200316 US9227956, 1

SMILES Cc1cccnc1N([C@@H]1CCCNC1)C(=O)c1ccc(cc1)-c1cnn2cccnc12

InChI Key InChIKey=BPKFNINHTCLDAF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 200316   

LigandChemical structure of BindingDB Monomer ID 200316BDBM200316(US9227956, 1)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 200316BDBM200316(US9227956, 1)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of full length human PCSK9 expressed in human Huh-7 cells by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 200316BDBM200316(US9227956, 1)
Affinity DataIC50: 3.20E+3nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
US Patent