BDBM200513 US9670231, 1.35

SMILES FC(F)(F)c1cccc(c1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12

InChI Key InChIKey=NQSNNAVTPSOCHY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 200513   

LigandPNGBDBM200513(US9670231, 1.35)
Affinity DataIC50: 0.330nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Beigene

US Patent
LigandPNGBDBM200513(US9670231, 1.35)
Affinity DataIC50: 1.20nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Beigene

US Patent
LigandPNGBDBM200513(US9670231, 1.35)
Affinity DataIC50: 9.70nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Beigene

US Patent
LigandPNGBDBM200513(US9670231, 1.35)
Affinity DataIC50: 18nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

LigandPNGBDBM200513(US9670231, 1.35)
Affinity DataIC50: 47nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent