BDBM200637 US9227977, Compound (Ia)
SMILES Nc1ncnc2n(Cc3nc4cccc(C#CCOCCOCCO)c4c(=O)n3Cc3ccccc3C(F)(F)F)nc(-c3cc(O)cc(F)c3)c12
InChI Key InChIKey=DNKXAAPJUKKDSI-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 200637
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
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Affinity DataIC50: 17nMAssay Description:As a means of assessing PI3K δ activation in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product of PI3K...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
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Affinity DataIC50: >1.42E+4nMAssay Description:As a means of assessing PI3K alpha or beta; activation in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product o...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
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Affinity DataIC50: >1.42E+4nMAssay Description:As a means of assessing PI3K alpha or beta; activation in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product o...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
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Affinity DataIC50: 577nMAssay Description:As a means of assessing the activation of PI3K γ in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product of...More data for this Ligand-Target Pair