BDBM200766 US9233111, 4

SMILES CC(C)N(C)c1ccc(cc1)C(=O)Nc1cc(F)cc(c1C)-c1ncnc2[nH]c(cc12)C1=CCN(CC1)C(=O)N(C)C

InChI Key InChIKey=DMNHSLASUQNFKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200766   

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM200766(US9233111, 4)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
US Patent