BDBM2012 Pyridobenzoxazepinone 80::methyl 10,14-dimethyl-9-oxo-2-oxa-4,10-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaene-12-carboxylate

SMILES COC(=O)c1cc(C)cc2Oc3ncccc3C(=O)N(C)c12

InChI Key InChIKey=MJMDFEZUPZGSHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2012   

TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2012(methyl 10,14-dimethyl-9-oxo-2-oxa-4,10-diazatricyc...)
Affinity DataIC50: 22nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2004
Entry Details Article
PubMed