BDBM201631 4-[2-(2h-pyrazol-3-yl)-6-(6-pyrrolidin-1-yl-pyridin-2-ylmethoxy)-pyrimidin-4-yl]-morpholine::US9540384, 23

SMILES C(Oc1cc(nc(n1)-c1ccn[nH]1)N1CCOCC1)c1cccc(n1)N1CCCC1

InChI Key InChIKey=TXAJAGIOIARHLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201631   

LigandPNGBDBM201631(4-[2-(2h-pyrazol-3-yl)-6-(6-pyrrolidin-1-yl-pyridi...)
Affinity DataIC50: 1.08E+3nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent