BDBM202030 6-chloro-5-methoxy-2-(2-(6-(pyrrolidin-1-yl)pyridin-2-yl)ethyl)-quinazolin-4(3h)-one::US9540384, 27

SMILES COc1c(Cl)ccc2nc(CCc3cccc(n3)N3CCCC3)[nH]c(=O)c12

InChI Key InChIKey=OMVDNDUJYIHISI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202030   

LigandPNGBDBM202030(6-chloro-5-methoxy-2-(2-(6-(pyrrolidin-1-yl)pyridi...)
Affinity DataIC50: 470nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent