BDBM202231 6-chloro-n,n-dimethyl-2-(2-(6-(2-methylpyrrolidin-1-yl)pyridin-2-yl)ethyl)quinazolin-4-amine::US9540384, 38

SMILES CC1CCCN1c1cccc(CCc2nc(N(C)C)c3cc(Cl)ccc3n2)n1

InChI Key InChIKey=ZOJRPJJGDXBJLU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202231   

LigandPNGBDBM202231(6-chloro-n,n-dimethyl-2-(2-(6-(2-methylpyrrolidin-...)
Affinity DataIC50: 81nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent