BDBM202236 (e)-5,8-dimethyl-2-(2-(6-(pyrrolidin-1-yl)pyridin-2-yl)vinyl)[1,2,4]triazolo[1,5-a]pyrazine::US9540384, 43

SMILES Cc1cnc(C)c2nc(\C=C\c3cccc(n3)N3CCCC3)nn12

InChI Key InChIKey=HMGKRIYGIBCCNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202236   

LigandPNGBDBM202236((e)-5,8-dimethyl-2-(2-(6-(pyrrolidin-1-yl)pyridin-...)
Affinity DataIC50: 12nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent