BDBM202286 3-methyl-n-((6-(pyrrolidin-1-yl)pyridin-2-yl)methyl)-2-(trifluoromethyl)imidazo[1,2-b]pyridazin-6-amine::US9540384, 57

SMILES Cc1c(nc2ccc(NCc3cccc(n3)N3CCCC3)nn12)C(F)(F)F

InChI Key InChIKey=XPDHTCOKZOJQCI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202286   

LigandPNGBDBM202286(3-methyl-n-((6-(pyrrolidin-1-yl)pyridin-2-yl)methy...)
Affinity DataIC50: 200nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent