BDBM202320 1-((4as,7ar)-6-(methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino)hexahydro-1h-cyclopenta[c]pyridin-2(3h,4h,4ah,5h,6h,7h,7ah)-yl)ethanone::US9527851, example 35

SMILES CN(Cc1ccccc1)C1C[C@H]2CCN(C[C@H]2C1)C(=O)OC(C)(C)C

InChI Key InChIKey=UFVUDSYXEFXWFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 202320   

TargetTyrosine-protein kinase JAK1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM202320(US9527851, example 35 | 1-((4as,7ar)-6-(methyl(7h-...)
Affinity DataIC50: 3nMpH: 7.3 T: 2°CAssay Description:TBDIn vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK1 kinase. The te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM202320(US9527851, example 35 | 1-((4as,7ar)-6-(methyl(7h-...)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK2 kinase. The test ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
US Patent